This editorial recaps on the achievements of Cushing’s Hub to date and highlights the latest additions to the content which include an exploration of the common complications of Cushing’s syndrome (see Varlamov EV, et al. Animated Abstract); the exciting advances in our understanding of the genetic basis of GIP-dependent PBMAH (see Chasseloup, et al. Publication Highlight); and the forthcoming Interactive Clinical Case by Dr Niki Karavitaki on the challenges of identifying Cushing’s patients.

Nelson’s syndrome (NS), or corticotroph tumour progression (CTP) after bilateral adrenalectomy (BADX) for Cushing’s disease, can be a challenging condition to manage. This editorial explores the recent expert consensus recommendations (Reincke et al. Eur J Endocrinol. 2021; 184(3):P1–P16) which encompass surveillance criteria, surgical approaches, and use of radiation therapy, as well as a change in terminology.

This editorial looks at highly important yet non-routine aspects of Cushing’s syndrome and encourages readers to consider elements of the disease where literature is scarce.  Topics include once-in-a-lifetime events necessitating hospitalization – sometimes before diagnosis is made – and practical advice on the use of steroidogenesis inhibitors. The editorial also highlights recent research on the effect of Cushing’s syndrome on pregnancy outcomes.

A website on Cushing’s syndrome? Why would I be interested in a website like that?

The Editorial Board Members describe the importance of a website dedicated to Cushing’s syndrome and the reasons they signed up for the project