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Unmet needs in Cushing's syndrome: the patients’ perspective
How do Cushing’s syndrome patients perceive the quality of their diagnosis and their management? Could we be doing better?
Valassi E, et al. Unmet needs in Cushing's syndrome: the patients’ perspective. Endocrine Connections. 2022;doi.org/10.1530/EC-22-0027. Open access.
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Metyrapone in Cushing's Syndrome
Six decades of clinical use, accompanied by number of prospective and retrospective studies, have established metyrapone as an effective treatment for Cushing's syndrome. What...
Al-Salama, ZT. Metyrapone in Cushing’s Syndrome: A Profile of its Use. Drugs Ther Perspect 2021. doi.org/10.1007/s40267-021-00853-y
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A challenge to the current methods of CD investigation
This review explains the recent work of Walia et al. 2021, who have used a novel imaging technique to correctly identify adenomas, some of which were negative on MRI or of ect...
Bertherat J. CRH-Receptor Molecular Imaging Reveals the Intimacy of Corticotroph Adenomas. J Clin Endocrinol Metab. 2021 106:e1902-e1904.
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Ga-68 corticotrophin-releasing hormone PET-CT
This novel, non-invasive molecular imaging technique potentially expands current diagnostic capabilities – will you investigate?
Walia R, et al. Molecular Imaging Targeting Corticotropin-releasing Hormone Receptor for Corticotropinoma: A Changing Paradigm. J Clin Endocrinol Metab. 2021 106:e1816-e1826
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Inferior petrosal sinus sampling
Findings from this literature review suggest using a stepwise approach to performing IPSS and interpreting the results. How might your practice be influenced?
Perlman JE, et al. Pitfalls in Performing and Interpreting Inferior Petrosal Sinus Sampling: Personal Experience and Literature Review J Clin Endocrinol Metab. 2021 106:e1953-...
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Hypercortisolism and atrial fibrillation
This study attempts to establish a causal relationship between hypercortisolism and AF but what were the precise findings and likely mediators?
Larsson SC, et al. Plasma Cortisol and Risk of Atrial Fibrillation: A Mendelian Randomization Study. J Clin Endocrinol Metab. 2021 106:e2521-e2526.
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