Case Studies

This module describes a case of Cushing’s syndrome in a 67-year-old woman, an age when disease characteristics may vary from those seen in younger patients.

This case study ꟷ the Cushing’s Hub Clinical Case Competition 2023 winning entry ꟷ looks at the clinical evaluation and management of MACS ranging from the assessment of adrenal incidentalomas to the development of an individual treatment plan.

This interactive case study describes a case of ectopic Cushing’s syndrome in a middle-aged woman presenting with severe back pain.

This interactive case study describes an unusual case of Cushing’s syndrome in a largely asymptomatic, female patient presenting with a fragility fracture.

This case study—the Cushing’s Hub Clinical Case Competition winning entry—looks at primary bilateral macronodular adrenal hyperplasia as a cause of Cushing’s with special emphasis on the role of aberrant receptors.

This module looks at the diagnostic strategy required to establish the cause of adrenocorticotrophic hormone (ACTH)-dependent Cushing’s syndrome, when imaging and biochemical results are inconclusive.

This module looks at the optimal way to manage hypercortisolism with associated comorbidities, particularly in patients who are ineligible for surgery.

This module raises questions about who should be screened for Cushing’s syndrome and considers the most suitable diagnostic tests for the avoidance of diagnostic uncertainty.

The third interactive case study describes patient follow-up after bilateral adrenalectomy and explains how to develop a treatment plan for an aggressive Nelson’s tumour.

The second interactive case study explores the management of relapsing Cushing’s disease in a woman of childbearing age with emphasis given to pregnancy planning.

This interactive training module uses a case study format to explore the optimal way to assess cortisolemia in patients who have started treatment for Cushing’s syndrome.